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Globulin and Total Protein
Globulin refers to a group of proteins in your blood that play key roles in immune response, inflammation, and hormone transport. Total protein measures both globulin and albumin combined. Abnormal protein levels may indicate malnutrition, liver dysfunction, or immune disorders. Monitoring these markers provides important context for evaluating immune health and liver function and can guide nutritional strategies.

Gamma-glutamyltransferase (GGT) and Alkaline Phosphatase (ALP)
These two enzymes are sensitive indicators of liver and bile duct health. GGT is often elevated in cases of alcohol-related liver damage or bile duct obstruction, while ALP rises in liver disease, gallstones, or bone disorders. When elevated together, they may indicate issues with bile flow or hepatobiliary inflammation. These markers are essential for evaluating liver performance and the body’s detoxification ability.

Triglycerides, HDL % of Total, Non-HDL Cholesterol, Total Cholesterol, HDL Cholesterol, and LDL Cholesterol
This lipid panel offers a comprehensive overview of cardiovascular health. Total cholesterol reflects all cholesterol types, while LDL (“bad” cholesterol) is linked to atherosclerosis. HDL (“good” cholesterol) helps remove cholesterol from the bloodstream and is protective. The HDL % of total gives an additional ratio-based insight into lipid balance. Non-HDL cholesterol includes all potentially harmful lipoproteins and is a strong predictor of heart disease risk. Triglycerides, meanwhile, reflect the body’s fat metabolism and are closely linked to insulin resistance and metabolic syndrome. This full profile helps guide lifestyle, diet, and cardiovascular prevention strategies.

Creatinine, Urea, and Estimated Glomerular Filtration Rate (eGFR)
These markers assess kidney function and how efficiently your body filters waste. Creatinine is a by-product of muscle metabolism, and urea comes from protein metabolism—both are excreted by the kidneys. eGFR calculates how well your kidneys are working and is key for identifying early-stage kidney disease. These markers are also influenced by hydration, muscle mass, and protein intake, and are essential for monitoring long-term renal health.

Ferritin
Ferritin is the primary storage form of iron in the body and reflects your iron reserves. Low ferritin levels may indicate iron deficiency before anaemia develops, while high levels can suggest iron overload, inflammation, or liver disease. Monitoring ferritin helps assess fatigue, poor exercise tolerance, and immune function and is an essential component of anaemia diagnosis.

Vitamin B12
Vitamin B12 plays a critical role in red blood cell formation, DNA synthesis, and neurological function. Deficiency may cause symptoms such as fatigue, memory problems, tingling sensations, and mood changes. Low levels are common in individuals with restricted diets, poor absorption, or gastrointestinal disorders. Monitoring B12 ensures healthy cognitive, nerve, and metabolic function.

Creatine Kinase (CK)
Creatine kinase is an enzyme found in muscles. It enters the bloodstream when muscle tissue is damaged, which can occur due to intense exercise, trauma, or underlying muscle disorders. Elevated CK levels are often temporary in athletes but may also point to muscle inflammation or rhabdomyolysis if significantly raised. It’s a key marker for assessing muscle stress and recovery.

Albumin
Albumin is the most abundant protein in plasma and is synthesised by the liver. It helps maintain fluid balance and acts as a carrier for hormones, medications, and nutrients. Low albumin levels can reflect liver disease, malnutrition, or chronic inflammation. Albumin is a standard marker of overall health and nutritional status, and changes may signal systemic illness.

Alanine Transferase (ALT) and Bilirubin
ALT is a liver enzyme that is released into the blood when liver cells are damaged. Bilirubin is a pigment processed by the liver after red blood cells break down. Elevated levels of either may suggest liver inflammation, hepatitis, or bile duct obstruction. Together, these markers are used to assess liver cell integrity and bile metabolism efficiency.

Vitamin D (25-Hydroxyvitamin D)
Vitamin D is essential for calcium absorption, bone strength, immune modulation, and muscle performance. Deficiency is widespread in the UK, especially during winter, and is linked to fatigue, bone pain, mood disturbances, and increased infection risk. Testing vitamin D levels helps guide safe supplementation and supports long-term bone and immune health.

hs-CRP (High-Sensitivity C-Reactive Protein)
hs-CRP is a highly sensitive indicator of systemic inflammation. Even mildly elevated levels are associated with increased risk of heart disease, type 2 diabetes, and autoimmune conditions. Unlike standard CRP tests, hs-CRP detects chronic, low-grade inflammation that may be asymptomatic but still clinically significant. It is a valuable tool for early disease prevention and lifestyle assessment.