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Oestradiol (Oestrogen)
Oestradiol is the primary form of oestrogen in premenopausal women and plays a vital role in regulating the menstrual cycle, supporting fertility, and maintaining bone, brain, and cardiovascular health. Oestradiol levels naturally fluctuate throughout the cycle but may be abnormally high in conditions like oestrogen dominance or certain ovarian cysts, or too low during menopause or with hypothalamic dysfunction. This biomarker is included to assess oestrogen status, monitor hormone therapy, and evaluate reproductive health. Imbalances in oestradiol can affect everything from mood and libido to menstrual regularity and ovulatory function.

Progesterone
Progesterone is produced by the ovaries after ovulation and is essential for preparing the uterus for potential pregnancy. Its levels rise during the second half of the menstrual cycle (luteal phase) and are a strong indicator of whether ovulation has occurred. Low progesterone may lead to short luteal phases, fertility issues, or irregular periods, while persistently high levels outside of pregnancy may indicate hormonal dysregulation. Measuring progesterone helps confirm ovulation timing and supports investigation into cycle irregularities, fertility status, or hormone therapy monitoring.

Prolactin
Prolactin is a hormone released by the pituitary gland that primarily regulates breast development and milk production. Elevated prolactin levels—known as hyperprolactinaemia—can interfere with ovulation, suppress other sex hormones, and cause menstrual irregularities or unexpected lactation. Common causes include stress, certain medications, or benign pituitary tumours (prolactinomas). This biomarker is essential for diagnosing underlying hormonal conditions that may impact fertility, libido, and menstrual health, especially when symptoms like breast discharge, missed periods, or low oestrogen are present.