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Chlamydia
Chlamydia trachomatis is one of the most common bacterial STIs in the UK. It often presents no symptoms but can lead to pelvic inflammatory disease (PID), infertility, and ectopic pregnancy if left untreated. In men, it can cause urethritis and potential complications with fertility. Screening is vital due to its prevalence and potential to silently damage reproductive health.

Trichomoniasis
Trichomoniasis is caused by the Trichomonas vaginalis parasite. While many individuals may remain asymptomatic, the infection can cause irritation, discharge, and discomfort, and it increases the risk of contracting other STIs, including HIV. Timely identification ensures effective treatment and reduces transmission.

Mycoplasma
Mycoplasma hominis and similar species are bacteria that can cause genitourinary infections, particularly urethritis, pelvic pain, and fertility issues. While often present without symptoms, persistent or recurrent infections can compromise urogenital health, particularly in women.

HIV (Types I, II, and P24 Antigen)
This test detects HIV-1, HIV-2, and the P24 antigen, which appears soon after infection. Early diagnosis of HIV is critical for effective treatment and reducing transmission. With antiretroviral therapy, individuals diagnosed early can manage the virus and live a long, healthy life. P24 testing is especially useful for identifying acute HIV infection before antibodies appear.

Hepatitis B
Hepatitis B virus (HBV) is a bloodborne infection that targets the liver. It can become chronic and increase the risk of cirrhosis or liver cancer if undetected. Hepatitis B is transmitted through sexual contact, blood, or body fluids. Testing ensures early medical intervention and prevents spread.

Mycoplasma Genitalium
This emerging STI is now recognised as a cause of non-gonococcal urethritis in men and pelvic inflammatory disease in women. It is often resistant to standard antibiotics, making detection crucial for correct treatment. According to Public Health England, it is increasingly seen in younger sexually active populations.

Gonorrhoea
Caused by Neisseria gonorrhoeae, gonorrhoea is a bacterial infection that can cause painful urination, discharge, and long-term complications like infertility and chronic pelvic pain. Many cases go unnoticed, especially in women, which highlights the importance of regular testing.

Gardnerella
Gardnerella vaginalis is a bacterium most often associated with bacterial vaginosis (BV). While not strictly an STI, BV is linked to increased susceptibility to STIs and complications during pregnancy. Identifying an overgrowth helps guide antimicrobial treatment.

Ureaplasma
Ureaplasma species can exist as part of the normal genital flora but are sometimes implicated in urethritis, infertility, and adverse pregnancy outcomes. Testing can help differentiate between colonisation and pathogenic infection, supporting targeted therapy if needed.

Syphilis
Caused by Treponema pallidum, syphilis progresses in stages and can cause serious systemic complications if left untreated, including neurological and cardiovascular damage. Early diagnosis is key, as it is highly treatable in the early stages. This test detects antibodies indicating current or past infection.

Herpes Simplex Virus I & II (HSV-1 and HSV-2)
HSV-1 commonly causes oral herpes, while HSV-2 is typically associated with genital herpes. However, both can be transmitted through sexual contact. This test identifies antibodies to determine prior exposure, which is essential as many people carry the virus without symptoms but may still transmit it.